Designs for Health Probiotic Synergy

Reviewed product: Designs for Health Probiotic Synergy

General score: 3/5 stars

Form of presentation: spheres

Serving dimensions: 8mm x 8mm

Cost: $37.90

Recommended dosage: 1 sphere/ day

Bottle content: 60 spheres

Daily cost: $0.63

Viability: through time of manufacturing

CFUs count: 5 billion CFUs

Ingredients: a proprietary blend of 8 probiotic strains, namely Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium breve, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus reuteri, Lactobacillus rhamnosus, and Streptococcus thermophilus

Customer satisfaction: not guaranteed

Product category: daily usage probiotic

Purchasing: via the manufacturer’s official website

General review

The Designs for Health Probiotic Synergy enhancer currently positions itself at a total rating of 3/5 stars, namely around the average mark for any similar dietary supplement.

Among the positive aspects which Probiotic Synergy displays is the practical nature of its administration schedule – with only one sphere to be taken daily, there is no worry you will forget about it or end up taking it ‘wrongly’ (since there is no particular specification whether the product should be ingested before/ after meals).

And, speaking of the probiotic spheres themselves, it should be mentioned that these are considerably smaller than most commercially distributed capsules and pills, with an 8mm x 8mm dimension ensuring for easy and stress-free swallowing (more so if you usually dread having to ingest bigger medicine formats).

In terms of probiotic potency, Probiotic Synergy encompasses 5 billion CFUs in 8 distinct ‘good’ bacteria strains. Since the human organism might need anything between 1-100 billion CFUs of beneficial microorganisms daily, this particular dosage can be the ideal balance between effectiveness and mildness of action for most, while the different probiotic types should ensure a larger spectrum of digestive and immune screening areas are covered with the help of one single product.

Other advantages of using Probiotic Synergy as your daily supplement are represented by the lack of side effects otherwise normally associated with probiotic administration – especially in the first few days of microflora ‘accommodation’.

In my personal experience, Probiotic Synergy did not generate any unwanted or painful outcomes throughout its entire utilization. In addition, this particular probiotic enhancer is non-GMO, gluten-free, and uses natural colours (turmeric) instead of artificial ones in its composition. These characteristics make it very allergen-friendly and even adaptable to a vegetarian or vegan lifestyle.

So, you might be asking yourself: if Probiotic Synergy is so amazing, then why the average score? Well, it also stands to be noted that the present product also has a number of drawbacks to its name.

Firstly, there’s the issue of manufacturer guarantees: not only does the company not offer a money-back policy unless you meet certain specifications (for instance, for the package to be unopened and returned within 30 days of ordering), but you also do not receive a compelling guarantee for the viability of the microorganisms themselves.

In fact, the manufacturer ensures probiotic viability only until the product leaves the factory, with exposure to various factors (light, humidity, heat, etc.) and lack of refrigeration slowly decreasing the enhancer’s potency. Needless to say, this is a big negative point to Probiotic Synergy, since this sort of supplements should be practical and viable throughout the expiration date, not fridge-bound and ‘more or less’ effective over time.

Another big issue with Probiotic Synergy is that, aside from the probiotic strains, it contains a rather large amount of fillers and additional ingredients (hydroxypropyl methylcellulose, pectin, microcrystalline cellulose, sodium carbonate, silica dioxide, etc.).

While not harmful, these substances detract from the product’s general ‘naturalness’, giving it the aspect of yet another pharmaceutical medicine instead of an organic boost for any individual’s wellbeing.

Consequently, Designs for Health Probiotic Synergy does present a good probiotic level (5 billion CFUs in 8 strains), few to none allergenic threats, and a special administration format (sphere).

Even so, it lacks satisfactory customer guarantee, extended practicality (needs refrigeration), and a more wholesome composition is to be desired, which hence places Probiotic Synergy at an average rating of 3/5 stars.

Detailed description

Ingredient list

Encompassing a CFUs (colony forming units) count of 5 billion microorganisms, Probiotic Synergy is mainly based on 8 distinct strains of ‘friendly’ bacteria, as follows:

Bifidobacterium bifidum – this member of the Bifidobacterium family can be naturally found inside the human body, where it promotes regular motility patterns, boosts immunity protection, and also generates overall wellbeing.

As an organic part of the small intestine, colon, and vaginal microflora, Bifidobacterium bifidum has the role of acting as an antimicrobial and pathogen repellent, as well as facilitating food decomposition and nutrient absorption at the level of the gut (particularly various types of sugars). As a result, the gastrointestinal system is screened against infections (like E. coli), diarrhea episodes, Candida overgrowths, etc.

Bifidobacterium longum – although not a prevalent component of the intestinal tract, Bifidobacterium longum plays an essential role in maintaining bowel motility patterns, immune protection, and mood stability.

By producing lactic acid, this ‘good’ bacterium screens the organism against harmful pathogens, with proper supplementation – either through probiotic foods or pharmaceutical derivates – leading to an improved status of gut microflora. As a ‘scavenger’, Bifidobacterium longum helps decompose tough to digest substances (for instance, amino acids), increases assimilation within the gastrointestinal system, and even speeds up recovery in the case of ulcerative colitis.

Bifidobacterium breve – as a fermentative bacterium, Bifidobacterium breve has the role of producing important quantities of lactic and acetic acid within the gut, hence generating improved digestion of otherwise difficultly processed substances such as carbohydrates. This particularity subsequently leads to enhanced nutrient absorption within the gastrointestinal system and considerably boosted immune responses in the long run.

In addition, the present Bifidobacterium genus member screens the body against pathogens such as Escherichia coli, a bacterium responsible with an array of negative outcomes for the body such as food poisoning, gastroenteritis, and urinary tract infections.

Lactobacillus acidophilus – this ‘superstar’ of the Lactobacillus family and probiotic world alike has been undoubtedly brought into the public eye by numerous commercials for natural yogurts and similar probiotic foods as well. With good reason too – for starters, its propensity to decompose ‘tough’ dairy variants and produce lactic acid enables for better lactose tolerance, facilitated food processing, and hence general visceral wellbeing.Secondly, Lactobacillus acidophilus accelerates microflora recovery after antibiotic-based treatments and shortens the duration of diarrhea episodes.

Moreover, this ‘good’ bacterium prevents a high pH and bile resistance, meaning it can remain alive and active inside the gut for longer periods of time and therefore promote general wholesomeness.

Lactobacillus casei – aside from ameliorated lactose tolerance and abdominal wellbeing, Lactobacillus casei can be a highly important instrument in combating Helicobacter pylori infections and Clostridium difficile colitis. As a probiotic, this microorganism generates regular digestive patterns and elevated immune screening, as well as having the potential to treat and cure various imbalances related to the intestinal microflora.

For example, antibiotic-induced diarrhea episodes can be shortened and ultimately eliminated through sustained administration of Lactobacillus casei, with even more serious health problems like pancreatic necrosis benefiting from the same positive effects brought about by this specific ‘friendly’ bacterium.

Lactobacillus reuteri – was first isolated in the 1980s and used via external supplementation as a means of improving both food decomposition processes and pathogen screening. As a probiotic pertaining to the Lactobacillus family, this beneficial microorganism relies on its lactic acid production to improve digestive rhythms and bowel movement regularity, as well as promote visceral comfort over time.

In terms of pathogen protection, Lactobacillus reuteri acts as an antimicrobial by generating natural antibiotics of the reuterin type (which suppresses the development of protozoa, fungi, and yeasts). Consequently, having this probiotic as a normal presence inside the gut’s microflora will bring only (physical and mental) benefits.

Lactobacillus rhamnosus – due to its ability to resist gut acid and bile, Lactobacillus rhamnosus can colonize the stomach and intestines for extended periods, hence allowing for improved digestion and pathogen protection.

Furthermore, this ‘good’ bacterium brings a wide array of other benefits to the human organism, including the elimination of peanut allergies in children, reducing the duration of diarrhea episodes, helping better manage respiratory infections, treating urinary tract infections, and managing atopic eczemas. Moreover, Lactobacillus rhamnosus has shown positive results in reducing symptoms generated by irritable bowel syndrome (or IBS) like intestinal permeability and visceral discomfort.

Streptococcus thermophilus – when it is not employed in the production of various dairy products such as yogurt, Streptococcus thermophilus can be used as an external source of probiotic supplementation in order to ameliorate lactose intolerance for individuals who are sensitive (by decomposing milk sugars and transforming them into the more easily digestible lactic acid).

Additionally, this probiotic has shown a great antimicrobial potential due to its high heat resistance and adaptability within the gut environment. Other advantages of Streptococcus thermophilus include reduced inflammatory responses and decreased duration of antibiotic-associated diarrhea.

Allergenic potential

At first glance, it would appear that Probiotic Synergy does not pose any allergenic threats. In fact, the labelling actually specifies this supplement is non-GMO and gluten free.

Add to this the other set of specified ingredients – namely hydroxypropyl methylcellulose, pectin, microcrystalline cellulose, sodium carbonate, silica dioxide, vegetable stearate, guar gum, turmeric (natural colour) – and it becomes clear that Probiotic Synergy encompasses a good probiotic capacity with little potential to cause any sort of major reaction otherwise associated with allergens such as eggs, lactose, peanuts, fish and shellfish, etc.

Overall cost

As previously specified, Probiotic Synergy comes in the shape of a $37.90 bottle containing 60 spheres. At a daily recommended dosage of 1 sphere, this quantity will last you approximately 2 months (60 days) and will bring you to an overall cost of $0.63 for each individual dosage. In financial terms, Probiotic Synergy presents an average price for a regular usage probiotic.

Taking into consideration that it also gives you a good probiotic boost in the form of 5 billion CFUs and 8 separate strains of ‘good’ bacteria, then the general cost-quality ratio of this specific product is a very advantageous one in the long run.

Side effects

Another ‘bonus’ point for Probiotic Synergy is the fact that it does not cause any major side effects during administration. From experience, I can attest that many probiotic supplements generate a sensation of bloating and abdominal pain – more so during the first days of usage – but it appears that Probiotic Synergy was mild enough not to create any such discomfort.

Since you only have to take one sphere daily, this probiotic can be considered effective and practical, yet ‘temperate’ enough so as to not meddle too much with your intestinal balance.

Manufacturer guarantee

On the other hand, Probiotic Synergy loses some ground when it comes to money-back guarantees, which are nowhere to be found (neither on the packaging and label or the official Designs for Health website).

This constitutes a major drawback for any quality probiotic supplement, since customer satisfaction should always be a top priority for companies which – after all – claim to cater to their users’ wellbeing. As such, claiming a refund can only be done if the product was unopened and returned within 30 days of purchasing, with an additional 10% restocking fee being charged from your part as well.

To make matters worse, the probiotic durability can also be questioned when discussing this product. The bottle label clearly states that ‘viable organisms are at time of manufacture’, meaning that you could be receiving a product containing no ‘good’ live bacteria to begin with, with additional refrigeration and no sunlight, humidity or heat exposure being needed to maintain the probiotics active over time. Overall, these disadvantages clearly take away from the supplement’s practicality and even effectiveness.


Designs for Health Probiotic Synergy can be acquired through the manufacturer’s official site.

Designs for Health Probiotic Synergy – general view

Category Designs for Health Probiotic Synergy
General rating 3/5 stars
Recommended usage Daily usage probiotic
Ingredients 5 billion CFUs, 8 probiotic strains
Allergenic potential Allergen-friendly
Cost $37.90 for 60 spheres (2 months’ worth of administration)
Side effects No noticeable side effects
Manufacturer guarantee(s) Not available
Purchasing Via the company’s main website


About the Author

Maya Caplin
Maya Caplin
My name is Maya Caplin and I am the creator of ProBiotics America. I love to write about probiotics. Why is that? Because I firmly believe that you can substantially improve your health by taking probiotics supplements. Your body craves beneficial bacteria so it can continue to function at peak levels. As a probiotics expert, I've created this website so you can easily access all you need to know about how to create your own probiotics lifestyle. It's easier than you think. Changing your thinking to include the importance of what you eat is fundamental to everything about a new lifestyle. That's where I come in. My strong belief is that given the right information about anything, and you will be able to make accurate decisions that will bring you the best benefits. Learning all you can about probiotics is my number one goal for you. It's what I do best, and what I want to give to you. Choose your best life, and stay informed. My research is always thorough and I stay informed so you don't have to do the hard work yourself. Just keep us bookmarked for the best in probiotic information you will ever receive.

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